Ondansetron : Nausea

SUDA’s ondansetron project is a first-in-class mint-flavoured oral spray formulation of ondansetron (marketed in tablet form by GlaxoSmithKline under the brand name Zofran®), the most commonly prescribed antiemetic to treat nausea and vomiting induced by chemotherapy or radiotherapy and also other post-operative settings.

This project achieves therapeutic drug levels by delivering a micro-mist of concentrated ondansetron over the oral mucosa and may offer a desirable alternative to patients requiring antiemetic therapy who have difficulty in swallowing.

SUDA has undertaken a Pivotal PK Clinical Study. A summary of the study highlighted:

  1. Rapidly absorbed via oral mucosa with detectable plasma levels immediately following administration
  2. Demonstrated bioequivalence with Zofran®
  3. Superior rate of absorption within the first 20 minutes
  4. Well tolerated with no signs of oral irritation

For further information about clinical studies, please contact:  acurtis@sudapharma.com

 

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